LXRβ/estrogen receptor-α signaling in lipid rafts preserves endothelial integrity
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چکیده
منابع مشابه
LXRβ/estrogen receptor-α signaling in lipid rafts preserves endothelial integrity.
Liver X receptors (LXR) are stimulated by cholesterol-derived oxysterols and serve as transcription factors to regulate gene expression in response to alterations in cholesterol. In the present study, we investigated the role of LXRs in vascular endothelial cells (ECs) and discovered that LXRβ has nonnuclear function and stimulates EC migration by activating endothelial NOS (eNOS). This process...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 2013
ISSN: 0021-9738
DOI: 10.1172/jci66533